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Zantac® Frequently Asked Questions

Frequently Asked Questions

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What are H2 blockers?

H2 blockers, or histamine 2 blockers, are a category of medication that blocks a type of histamine, which is one of many stimulants of acid production in the stomach. H2 blockers, such as Zantac®, prevent or relieve heartburn by reducing the production of stomach acid.
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What are PPIs?

PPIs, or proton pump inhibitors, are a category of medication that inhibits, or stops, the secretion of acid in the stomach from the “proton pump,” a molecule contained in stomach cells which “pump” acid into the stomach.

Product examples of PPIs are presciption PPIs like Nexium®, Prilosec and Prevacid®, and over-the-counter PPIs like Nexium® 24HR, Prilosec OTC®, and Prevacid® 24HR.

Brands are the property of their respective owners.
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What are the differences between H2 blockers and PPIs?

While both H2 blockers and PPIs reduce the production of acid in the stomach, there are a variety of differences.

PPIs are used for frequent heartburn, taken daily as a regimen for 14 days. They are not indicated for immediate relief of heartburn.

H2 blockers like Zantac can be taken when needed for heartburn relief in 30 to 60 minutes, or heartburn prevention when taken 30 to 60 minutes before eating or drinking.
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Should I be concerned about the recent news of safety risks associated with prescription PPIs like Nexium, Prilosec and Prevacid?

No, Zantac is not a PPI.
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What is the active ingredient in Zantac®?

The active ingredient is ranitidine.
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What time of day should I take Zantac®?

Zantac® can be taken 30 to 60 minutes before eating food or drinking beverages that cause heartburn to prevent symptoms, or it can be taken when heartburn symptoms strike, providing relief in as little as 30 minutes* and controlling acid for up to 12 hours.
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Is it safe to use Zantac® on a daily basis?

You may take up to two (2) Zantac® tablets a day. Stop use and ask a doctor if you need to take this product for more than 14 days.
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How do I use Zantac®? Can I chew or crush the tablets?

Zantac® can be taken with water but should be swallowed whole. The tablets must not be chewed or crushed.
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Should I take the Zantac® before or after eating?

Zantac® can be taken either 30 to 60 minutes before eating to prevent heartburn or after the onset of symptoms to relieve heartburn.
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How does Zantac® work? How long will it take before I experience relief?

Zantac® relieves heartburn in 30 to 60 minutes and controls acid for up to 12 hours.

What are H2 blockers?

H2 blockers, or histamine 2 blockers, are a category of medication that blocks a type of histamine, which is one of many stimulants of acid production in the stomach. H2 blockers, such as Zantac®, prevent or relieve heartburn by reducing the production of stomach acid.

What are PPIs?

PPIs, or proton pump inhibitors, are a category of medication that inhibits, or stops, the secretion of acid in the stomach from the “proton pump,” a molecule contained in stomach cells which “pump” acid into the stomach.

Product examples of PPIs are presciption PPIs like Nexium®, Prilosec and Prevacid®, and over-the-counter PPIs like Nexium® 24HR, Prilosec OTC®, and Prevacid® 24HR.

Brands are the property of their respective owners.

What are the differences between H2 blockers and PPIs?

While both H2 blockers and PPIs reduce the production of acid in the stomach, there are a variety of differences.

PPIs are used for frequent heartburn, taken daily as a regimen for 14 days. They are not indicated for immediate relief of heartburn.

H2 blockers like Zantac can be taken when needed for heartburn relief in 30 to 60 minutes, or heartburn prevention when taken 30 to 60 minutes before eating or drinking.

Should I be concerned about the recent news of safety risks associated with prescription PPIs like Nexium, Prilosec and Prevacid?

No, Zantac is not a PPI.

What is the active ingredient in Zantac®?

The active ingredient is ranitidine.

What time of day should I take Zantac®?

Zantac® can be taken 30 to 60 minutes before eating food or drinking beverages cause heartburn to prevent symptoms, or it can be taken when heartburn symptoms strike, providing relief in as little as 30 minutes* and controlling acid for up to 12 hours.

Is it safe to use Zantac® on a daily basis?

You may take up to two (2) Zantac® tablets a day. Stop use and ask a doctor if you need to take this product for more than 14 days.

How do I use Zantac®? Can I chew or crush the tablets?

Zantac® can be taken with water but should be swallowed whole. The tablets must not be chewed or crushed.

Should I take the Zantac® before or after eating?

Zantac® can be taken either 30 to 60 minutes before eating to prevent heartburn or after the onset of symptoms to relieve heartburn.

How does Zantac® work? How long will it take before I experience relief?

Zantac® relieves heartburn in 30 to 60 minutes and controls acid for up to 12 hours.

*relief in 30-60 minutes


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